Fig. 3

Forest plot of Mendelian randomization and Bayesian Model Averaging Mendelian Randomization method of the effect of lipidomes on ER.⁻BC. The OR, P-val, and 95% CI are results obtained from the IVW method, while P-adj represents the outcomes adjusted via the FDR method. The B-OR and B-Pval are results derived from the MR-BMA analysis, and the forest plot displays the IVW results. (Sterol ester (27:1/20:4) refers to a specific type of sterol ester lipid molecule. In this case, the notation "27:1/20:4" denotes the fatty acid composition of the two acyl chains attached to the sterol backbone in the sterol ester molecule. For the "27:1" component, it indicates that one of the fatty acid chains contains 27 carbon atoms and one double bond, which is commonly seen in monounsaturated fatty acids like oleic acid. For the "20:4" component, it specifies that the other fatty acid chain contains 20 carbon atoms and four double bonds, which is characteristic of polyunsaturated fatty acids like arachidonic acid)